Chapter 628 Animal Experiments (2)(1/2)
How many steps does it take to have a child?
Answer: Three steps.
The first step is to find a beautiful woman.
The second step is to use means to get her pregnant.
The third step is to let her give birth to the child.
In Boss Shen's case, the same goes for pharmaceuticals.
For example, the hepatitis B vaccine was developed last time.
The first step is to decide to get a vaccine.
The second step is to set up a project team.
The third step is that the vaccine is ready.
The current drug for treating leukemia follows similar steps.
The first step is to decide to take leukemia treatment drugs.
The second step is to establish a research and development project team.
The third step is to prepare the medicine.
Now it's time to verify the effectiveness of this drug.
Once the medicine is released, this is a very big stage victory!
At least, it's not half done.
The celebration of the phased results ended successfully at the Jingcheng Hotel.
Everyone enjoyed an American-style party and a Chinese-style meal, and felt that the trip was worthwhile.
Except for veal, everyone is addicted to beef and steak.
In fact, the calf didn't eat less, he just didn't admit it.
He himself said that he drank only Coca-Cola and was so drunk that he couldn't remember anything.
Everyone gets drunk even if they are not drunk. Many people did stay in the hotel that night, and the waiter had to wash the sheets the next day.
However, no one needed to remind us the next day, everyone returned to their respective jobs early.
You can't slack off at this time, it's not yet time to relax.
The work plan has also been formulated in advance.
Shen Guanglin couldn't come, so everyone knew what they were going to do next.
The next step is to find enough derivatives and try them one by one.
This is the stage where you start spending money.
According to the pharmaceutical plan given by Pfizer, in terms of normal drug research and development, at this stage, they have already reached the middle stage of pharmaceutical production.
There are only a few steps left before the end.
For example, developing a reasonable production process for pharmaceuticals is one step.
For example, conducting animal experiments is also a step.
For example, Phase I clinical trials, Phase II clinical trials, and Phase III clinical trials are also considered one step.
Until the drug is actually put into use, it still needs to be optimized while being produced.
In fact, at this stage, if they want to get the drug on the market as soon as possible, the research team can already conduct animal experiments on the drug while developing derivatives.
After all, any derivative can only enter the next stage of clinical trials if it has been fully tested on animals.
Before using medicines on people, everything must be treated with caution.
In fact, for any new drug development cycle, 3 or 5 years is a relatively short cycle, and 10 years is not a long time.
10 years ago, I didn’t know you. 10 years later, you don’t belong to me.
Such situations are too common.
There are countless examples of failure, and there are always more examples of failure than success.
The people in Shen Guanglin's laboratory were so optimistic that Williams couldn't bear to interrupt them and tell them the truth.
Could it not go well?
After all, it has only been three months since the leukemia research team started working hard.
Even if the time period for preliminary research is included, it will only be half a year at most.
It takes half a year to make a medicine. Is it awesome?
Many people believe that at this stage, drug research and development will be considered successful.
If Shen Guanglin is brave enough, at this stage, he can really give this medicine to others.
The effect is definitely there, regardless of whether there are any side effects.
In the domestic environment, there are not many cases where a dead horse is used as a living horse doctor.
No, all those who have difficult and complicated diseases that cannot be cured by Western medicine will eventually seek help from Chinese medicine.
There is really no other way.
What can Chinese medicine do? We can only cross the river by feeling the stones.
Based on the theory of traditional Chinese medicine and free expression, Hu combined some medicines. Whether it works or not depends on fate.
In the West, it is extremely difficult to successfully develop an original drug.
Now, if Shen Guanglin announces that he has successfully developed a specific drug for leukemia, then the teams of other pharmaceutical companies in the world can really hang themselves.
Of course, according to normal progress, there is still a long way to go before leukemia treatment drug research reaches this stage.
After all, pharmaceuticals are different from vaccine research and development, and pharmaceuticals are still more complicated.
Shen Guanglin's laboratory produced the hepatitis B vaccine within two weeks. Although everyone was surprised, they thought it was reasonable.
After all, vaccine research is relatively simple, especially when there is already a successful precedent.
The Shen Guanglin Laboratory's so-called development of a hepatitis B vaccine is, to put it bluntly, just a repeated experiment.
Although they also have a complete set of procedures to verify the effectiveness, they feed it to pigeons, feed it to mice, taste it to rabbits, give it to dogs, and drink it in monkeys. In short, they have done various animal experiments.
But that's all just a process.
None of these animals were wasted, and the monkeys did not eat them. They were sent to the zoo at Shen Guanglin's initiative.
All the other animals were eaten by them, and nothing was wasted. Even the mice were not wasted. They were just as delicious when roasted, and they were grown in a laboratory and were very clean.
Many people say that the reason why their laboratory's hepatitis B vaccine was successfully developed is, in the final analysis, that they have just gone through the same path that others have taken, based on the success of others.
Everyone knew from the beginning that there would be no problems, and indeed there were no problems later.
In short, it is okay for Citigroup Merck Pharmaceuticals to do this, but it makes no sense for their Shen Guanglin Laboratory to do this.
The rapid development of hepatitis B vaccine by Shen Guanglin Laboratory only shows that they have done well by repeating experiments.
From the outside world, the development of leukemia treatment drugs is no longer a simple repetition of experiments. It is groundbreaking research.
Moreover, this is a great breakthrough.
A new breakthrough from pharmaceutical principles to engineering practice.
This is the world's first gene therapy drug, and everyone is waiting to see if this theory can work.
This is why when Shen Guanglin said he was short of money, countless pharmaceutical companies were willing to help.
A disease caused by gene expression, the cause of the disease has been found, and now they want to stop the genetic mutation at the genetic level.
The idea is bold, but whether it will work or not is unknown.
However, here at Shen Guanglin, all this is still a repeated experiment.
In the previous life, Novartis had successfully developed imatinib, using this method and this target.
Shen Guanglin's laboratory just repeated experiments without knowing any successful precedents.
In fact, many pharmaceutical companies, including Pfizer, have extremely deep desires and fears for truly original drugs.
After all, even for a company as big as Pfizer, new drugs are not released every year, especially original drugs.
You must know that it is very difficult to successfully develop a drug from the beginning of the project, and nine times out of ten it will fail.
However, after it is successfully launched, it can bring a profit period of up to twenty years, and some will also have an exclusive sales period of about seven years.
How much money can you make after such a wave?
Shen Guanglin himself is also thinking about how much money he can make if this drug is developed?
Without the need for others to answer, he knew the result himself: before the patent expires, the final sales volume that can be completed is 50 billion US dollars.
As for pharmaceutical costs?
To be continued...