After Tanglou returned to the dormitory, he directly redeemed and upgraded to the Animal Experiment Theory (two stars, 9), and then began to write the paper "The Effect of Cyclophosphamide (ide, CP) and Colchicine (e, COL) on

Traditional Kunming white mouse chromosome aberration experiments and theoretical research on breeding improved ICR mouse inbred strains."

Under the two-star technique, Tanglou wrote a paper of more than 6,000 words very fluently. After the paper, Tanglou theoretically discussed the experimental method of improving mice and created a new system.

And it focuses on the character advantages of the new generation of improved ICR mice, which have good maternal qualities, particularly docile temperament, strong physique and rapid growth.

After finishing the paper, Tang Lou directly submitted this theoretical research to the magazine "Cell".

"Cell", "Nature" magazine (Nature), and "Science" magazine (Sce) have become the three most authoritative journals in the world.

These three major journals are the journals where most scientific researchers are most looking forward to having their work published. Nature and SCE, two old journals, publish articles in a wider range of disciplines.

Since its inception in 1976, "Cell" has become one of the most famous journals in the field of natural science research in the world. "Cell" mainly publishes original scientific research reports of great significance, including many of the most important discoveries in the field of life sciences.

All published in "cell".

For example, the very famous "artemisinin" in China was discovered in the Chinese Herbal Medicine Garden. This article was published on it. It was through this method that Tu Aao and her colleagues caused a huge sensation in the world.

For another example, another very famous article analyzed the relationship between the genome of ethnic groups and the complex architecture of human diseases, arguing that a large amount of data obtained by whole-genome sequencing, the 1000 Genomes Project, and targeted genome sequencing revealed a wealth of rare diseases.

, individual mutations, which may indicate that recent mutations have a greater impact on disease susceptibility and protection than mutations that appeared in ancient times.

Many important research results have been published on it by many of the world's leading figures.

After Tanglou submitted the manuscript, he began to design his own topic and then reported to Professor Liu.

...

...

At the same time, on the other side of the ocean, at the "Cell" magazine in the United States, an editor received a paper submission from China. After reading it, he found it very interesting. If the ICR mouse inbred strain proposed by this author could

, is as good as what he introduced, it can completely replace the current white mice in the experimental animal world and become the gold standard in the industry.

This was an epoch-making event. The editor smelled something unusual and immediately printed out the paper and walked into the editor-in-chief Alex's office.

Alex, who is over 60 years old this year, has eye-catching golden hair and strong facial lines like a knife. His whole person gives people a sense of authority, and he is reviewing some papers very seriously.

Alex is very well-known and influential internationally, and his resume is also shining. He just retired from his position as a technical consultant for Johnson & Johnson Pharmaceuticals and joined "Cell" magazine. He is an extremely prestigious person.

, is also a very courageous editor-in-chief, and is also the director of the research institute affiliated to "cell".

Seeing the young editor knocking on the door and coming in, Alex raised his head and seemed a little dissatisfied: "Didn't I say that I have been selecting the cover articles for the next issue of the journal these two days? If there is nothing important, don't come in and disturb me."

The editor handed over the printed manuscript of the paper in his hand: "Editor-in-Chief, this paper is very interesting. I think you will be interested in it."

The editor is very familiar with Alex's temper. He is full of passion and sensitivity for such groundbreaking papers and research.

Alex was a little surprised. He took the paper from the little editor and took a look at the author. He was a doctor from China. He was a little surprised. Then he opened the content and read it carefully.

After reading it quickly, Alex put down the paper, pondered for a while, then picked it up and read it again.

"The characteristics of the ICR mouse inbred strain exceed those of all inbred strains cultivated in the world. If this could really be achieved, it would probably cause a sensation in the animal experiment world."

With Alex's knowledge, he certainly understands the influence of this paper, which is absolutely epoch-making.

More than two-thirds of animal experiments use mice, so an inbred mouse strain with better traits and more stability is enough to make all pharmaceutical companies and scientific research units crazy about it.

"Cell" journal, in addition to its editorial department, also has a subordinate research institute with part-time experts and researchers in various disciplines. It is a top scientific research institution in multi-disciplinary fields.

The institute's funding sources come from various pharmaceutical giants such as Pfizer, Johnson & Johnson, and GlaxoSmithKline, which are very authoritative in the world.

After reading Tanglou's paper, Alex had a crazy idea in his mind, which was to conduct verification tests through the cell's affiliated research institute. As long as the excellent characteristics of the ICR mouse inbred strain were confirmed, he would immediately start creating animals.

A new gold standard for testing inbred mouse strains in the experimental field, an authoritative new international standard.

From now on, all mice produced by animal companies must use ICR mice as the standard.

Alex thought for a while and said directly: "Print ten copies of this paper, and at the same time notify all the heads of the institute to be present. I want to hold a large-scale academic exchange meeting of the institute."

...

...

At this time, Tanglou had already compiled the first draft of his project.

When we arrived at Professor Liu Juzi's office and saw Tanglou, Professor Liu was certainly looking forward to it.

"Tanglou, how are you preparing for your project?"

Tanglou directly handed his first draft to Professor Liu and said: "Professor Liu, I have changed my mind. I am going to put down the topic of research and development of high blood pressure drugs. This time the topic I proposed is: "In the laboratory, for

Study on the evaluation of the characteristics, stability and superiority of the improved ICR mouse inbred strain compared with the traditional Kunbai mouse strain"

"ICR mice?"

Professor Liu was a little confused. She was naturally very familiar with the field of animal experiments, but she had never heard of an inbred strain of ICR mice.

"The so-called improved ICR mouse is a new inbred strain that I plan to study and improve in this project."

Tanglou said very directly.

"Are you going to improve experimental mice and then evaluate and study the characteristics, stability, and superiority of this mouse?"

Professor Liu was once again shocked by Tanglou. Why does this kid have such wild ideas?

"Professor Liu, actually I already have a preliminary theoretical research foundation. Now I need to induce the first batch of ICR mice in the laboratory. I have established a cooperation agreement with the Jin Group in Shanghai, and the other party has provided me with five hundred

As long as the first batch of mice can leave the laboratory, I will be able to breed a large number of ICR mice in the Jin Group's experimental base. For this project, I want all the teachers and students in the school to cooperate with me.

These ICR mouse inbred lines were scored and evaluated."

"I am willing to provide 100,000 improved ICR mice to the college for free. I will also fund the entire project at my own expense. The only requirement is that my laboratory be provided to induce the first batch of mice."

Tang Lou directly showed his trump card.

To be honest, for the teachers and students of the college, the general project funds are only 20,000 to 30,000 yuan, and the experimental mice often take up 5,000 to 6,000 yuan. If someone can provide mice for free, of course they are very willing.

In itself, this kind of evaluation experiment is very simple to operate. All that is required is to record the performance of the ICR mice during the experiment.

The final huge data will be compiled and analyzed by Tanglou itself.

Professor Liu was a little excited when he heard Tanglou's plan. This guy Tanglou was too daring to think, and he was also very maneuverable.

But the only question is whether this so-called improved ICR mouse is worth spending so much energy and mobilizing the entire school's teachers and students for evaluation.

If the ICR mouse inbred strain is not as good as Tanglou imagined, all follow-up work will be just a waste of time.

And this subject will also become a huge laughing stock.

"Tanglou, I'm going to ask the other instructors for their opinions on this project plan of yours. I need to digest it. It just so happens that you still have some time to prepare your proposal report, so I'll be here today."

Professor Liu waved his hand to let Tanglou go out first.
Chapter completed!